Several clinical scores, which are commonly based on the preoperative carcinoembryonic antigen (CEA) value, resection margin, primary tumour site, tumour TNM stage (T: the size of the origin and whether it has invaded nearby tissue; N: nearby lymph nodes that are involved; M: distant metastasis), lymph node metastasis, and tumour size, are designed to evaluate the status and predict the prognosis of patients with CRLM (Nordlinger et al., 1996; Fong et al., 1999; Kattan et al., 2008). The gene discussed is CEACAM5; the disease is neoplasm.