Figures 5A, B show KEGG pathways that were enriched in the training group, such as the cytosolic DNA sensing pathway, intestinal immune network for IgA production, T-cell receptor signaling pathway, RIG I-like receptor signaling pathway, primary immunodeficiency, B-cell receptor signaling pathway, Hedgehog signaling pathway, Notch signaling pathway, p53 signaling pathway, and TGF-β signaling pathway. Here, TGFB1 is linked to inborn error of immunity.