The multivariate Cox regression analysis validated that high SNRPA protein level was an independent risk factor for OS ((aHR (95%CI) 1.724(1.011-2.939), P = 0.045) and/or RFS (aHR (95%CI) 1.672(1.062-2.631), P = 0.026) in the HCC cohort (Table 3). This evidence concerns the gene SNRPA and hepatocellular carcinoma.