PDIA2 and cancer: Subcutaneous cancers became visible at 2 weeks after the transplantation of all types of cells; the tumor sizes developed from Wt (77.0 ± 14.7 mm2) and control RNAi cells (65.9 ± 6.7 mm2) were comparable but were over 2-fold larger than those developed from PDIA2-knockdown cells (33.3 ± 2.9 mm2).