BEX4 and glioblastoma: Subsequently, multivariate Cox regression analysis indicated that BEX1 (hazard ratio [HR]: 0.5; p < 0.001), BEX2 (HR: 1.38; p = 0.029), and BEX4 (HR: 0.2; p < 0.001) exhibited an independent prognostic value for GBM (Table 1).