Then, they co-cultured A549 cells with BMSC-EVs expressing miR-126-3p, and detected the expression of PTPN9 in A549 cells and the effect of miR-126-3p in BMSC-EVs on the occurrence and development of tumor cells, and found that overexpressing miR-126-3p -126-3p BMSC-EVs can inhibit the viability, invasion and migration of non-small cell lung cancer by inhibiting PTPN9 (45). This evidence concerns the gene PTPN9 and non-small cell lung carcinoma.