The KYSE30 and KYSE410, which displayed a moderate increase and an apparent decrease in C12orf59 levels, while the TE-1 and KYSE510, which exhibited intense increases in C12orf59 levels (Figures 1E, F), were subjected to lentiviral infection with either C12orf59-flag overexpression or C12orf59-shRNA interference. The gene discussed is TMEM52B; the disease is infection.