Tumor cells infected with NDV can cause the release of cytokines such as IFN-α, IFN-β, and TNF-α, which activates the NF-kB signaling pathway, which in turn stimulates the exogenous apoptotic pathway (Wilden et al., 2009; Elankumaran et al., 2010). Here, IFNB1 is linked to neoplasm.