NFKB1 and Parkinson disease: In mice or BH-SY5Y microglia induced in vivo and in vitro PD models, it was found that inhibition of lncHOXA11-AS inhibited neuroinflammation by upregulating miR-124-3p-follistatin-like 1 by suppressing the NF-κB pathway, and both of these ncRNA alterations significantly suppressed microglial cell activation and thus attenuated the development of PD (Cao et al., 2021).