Meanwhile, ETV5 expression had significantly positive correlations with CD8+ T cells (rcoad = 0.326, rread = 0.369), macrophages (rcoad = 0.228, rread = 0.271), DCs (rcoad = 0.342, rread = 0.332), and CAFs (rcoad = 0.286, rread = 0.365) both in colon and rectal cancer. This evidence concerns the gene CD8A and rectal cancer.