Interestingly, we found that CCR10, QRFPR, and UHRF1BP1 are upregulated in obesity OA samples compared to normal samples and in obesity OA samples compared to obesity non-OA samples, but LENG8 and HLA-DRB4 are downregulated (Figures 4(a) and 4(b)). Here, QRFPR is linked to obesity due to melanocortin 4 receptor deficiency.