Based on our results, there were no differences in maturation rate, fertilization rate, high-quality embryos rate, cleavage rate, implantation rate, oocytes morphology, or clinical IVF/ICSI outcomes between the PCOS and the control women either during the GnRH agonist protocol or the GnRH antagonist one. The gene discussed is GNRH1; the disease is polycystic ovary syndrome.