In addition, we do not think that this effect is specific to PCOS subjects but to all high responders, as Nejabati et al. [29] also could not detect any significant differences in FF PlGF levels between poor responders, normo-responders, and high responders when the provided gonadotropins doses were significantly lower between high responders vs poor responders and high-responders vs normo-responders. Here, PGF is linked to polycystic ovary syndrome.