In the “cancer group”, the contents of HP and PDIA3 were 164 ± 33 μl/ml and 74 ± 18 ng/ml respectively; in the “polyp group”, the above two contents were 137 ± 13 μl/ml and 61 ± 13 ng/ml respectively; in the “group of healthy volunteers”, the two contents were 138 ± 8 μl/ml and 58 ± 15 ng/ml respectively. This evidence concerns the gene PDIA3 and polyp.