F8 and hemophilia A: In low-income countries, most patients are underdiagnosed, resulting in patients dying prematurely due to a lack of treatment [2]. Hemophilia is mainly classified into three groups: hemophilia A, hemophilia B, and hemophilia C. Hemophilia A, B, and C result from deficiency or dysfunction of FVIII, FIX, and FXI, respectively.