Different biomarkers have been investigated in COVID-19, including C-reactive protein (CRP), procalcitonin (PCT), interleukin-6 (IL-6), and soluble urokinase-type plasminogen activator receptor (suPAR).6, , -9 These biomarkers are involved in different inflammatory pathways and are elevated in different kind of infections and have also been incorporated in different prediction models of disease severity or mortality.10,11. This evidence concerns the gene IL6 and infection.