Considering these reports, a cohort study in a Spanish population found three variants of the mortalin gene (two missense-R126W and P509S and a 17 kb insertion in intron 8) in PD patients and the German cohort found a mutation in mortalin gene-A476T (De Mena et al., 2009; Burbulla et al., 2010). Here, HSPA9 is linked to Parkinson disease.