Most cancer hallmarks, such as hypoxia, EMT, angiogenesis, TNFα pathway, PI3K-AKT-mTOR pathway, MYC pathway, and glycolysis pathway were enriched in Cluster B and RMScore-high group, while more infiltrated immune cells were enriched in Cluster A and RMScore-low group, which might account for the different prognosis. This evidence concerns the gene MYC and cancer.