AKT1 and cancer: As shown in Figure 3(b), most cancer hallmarks, including hypoxia, epithelial–mesenchymal transition (EMT), angiogenesis, TNFα pathway, PI3K-AKT-mTOR pathway, E2F targets, G2M checkpoint, MYC pathway, and glycolysis pathway were enriched in Cluster B, which had a poor prognosis.