DRD1 and psychiatric disorder: The cannabinoid CB1 receptors, as the target of THC, are present at very high levels on inhibitory (GABAergic interneurons) and at a lesser extent on excitatory (glutamatergic) terminals (36), as well as on neurons expressing dopamine D1 receptors, playing a specific role in the repertoire of different emotional behaviors included social and cognitive activity, which are affected in psychiatric disorders (37–40).