Steatosis can arise as a result of caloric overload, which dysregulates hepatocyte bioenergetics and metabolism (3) and increases reactive oxygen species (4) and hepatic triglyceride accumulation (5, 6), resulting in organ damage indicated by elevated plasma alanine aminotransferase (ALT) and aspartate aminotransferase (AST) (4, 7–11). This evidence concerns the gene GPT and steatosis.