Intriguing in the light of the postulated cell-of-origin in Burkitt lymphoma—a germinal center B-cell poised to express IgA [79, 82]—and it’s pathogenesis are the reduced serum IgA levels in patients with KS and mouse models [83–85] and the smaller and reduced number of Peyer’s patches reported in one study [83]. The gene discussed is CD79A; the disease is Burkitt lymphoma.