The outcomes illustrated that TACC3 had a positive association with the infiltrating levels of dendritic cell (r = 0.006, P = 8.87e − 01), neutrophils (r = 0.101, P = 2.64e − 02), and CD4+ T cell (r = 0.058, P = 2.02e − 01), but negatively correlated with tumor purity in LUAD (r = −0.035, P = 4.39e − 01), infiltrating levels of macrophages (r = −0.009, P = 2.64e − 02), CD8+ T cells (r = −0.066, P = 1.46e − 01), and B cells (r = −0.083, P = 6.85e − 02). The gene discussed is CD8A; the disease is neoplasm.