As per the results from the CIBERSORT algorithm, it was discovered that the proportions of activated NK cells, resting NK cells, follicular helper T cells, CD4 memory activated T cells, CD8+ T cells, plasma cells, M0 macrophages, M1 macrophages, and M2 macrophages were considerably elevated in LUAD tumor tissues with an increased TACC3 expression. The gene discussed is CD8A; the disease is neoplasm.