Bax and Bcl-2 are important biomarker proteins of apoptosis [22]; we examined the expression of these proteins in cirsilineol-treated prostate cancer cells and found that cirsilineol suppresses the expression of Bcl-2 and enhances the expression of Bax further confirming the induction of apoptosis in prostate cancer cells. This evidence concerns the gene BAX and Familial prostate cancer.