According to the research, YPFP plays an antiallergic role mainly through inhibiting inflammatory infiltration, regulating neuroinflammation, regulating fever, inhibiting vascular endothelial growth, and improving lipid storage, involving malaria, African trypanosomiasis, inflammatory bowel disease (IBD), allograft rejection, graft-versus-host disease, IL-17 signaling pathway, asthma, leishmaniasis, pertussis, Chagas disease (American Trypanosomiasis) and Rheumatoid arthritis and other signaling pathways. The gene discussed is IL17A; the disease is graft versus host disease.