Based on our evaluation of indicators in the articles selected for this study, the most common topics in AD papers focused on Aβ peptide protein deposition and metabolism, neuroinflammation, oxidative stress, apoptosis, synaptic plasticity, tau phosphorylation, neurotransmitters, and brain-derived neurotrophic factors, glucose metabolism, brain responses, and autophagy. The gene discussed is MAPT; the disease is Alzheimer disease.