ACSL4 and neoplasm: Then, high GPX4 expression was significantly correlated with lymph‐node metastasis (p = 0.029), tumor with low NOX1 expression tend to be higher pathological T stage (p = 0.001) and low expression of FACL4 was statistically correlated with higher M stage, besides, all the three markers expression were clinically correlated with primary tumor size (all p = 0.001).