The ApoE status was ɛ2/ɛ3 in the index multiple system atrophy case IV22, ɛ3/ɛ4 in her cousin with Parkinson’s disease with dementia (IV25) and ɛ3/ɛ3 in the other family member with Parkinson’s disease (III12). The gene discussed is APOE; the disease is Parkinson disease.