IL1B and Peri-Implantitis: (2020) with a sample of 318 Chinese patients, the authors observed that subjects carrying the T allele of IL-1A -889 and IL-1B +3954 had a significant 2.27–2.47-fold and 1.9–1.99-fold increased risk of peri-implantitis, respectively, when using the CC genotype as reference.