In particular, hyperactive neuronal apoptosis, being a result of various cellular events, such as Aβ deposition, tau hyperphosphorylation, Bcl2, Bax, and caspases activation, neuroinflammation, and oxidative stress, can also lead to deleterious neurodegenerative disorders such as AD or PD [35]. The gene discussed is BCL2; the disease is Alzheimer disease.