Similarly, Marini et al. found a higher proportion of PMN-MDSCs (CD66b+ CD33dim HLA-DR-) in 124 patients with B-cell lymphoma (both HL and B-NHL) and that this was correlated with international prognostic index and disease status, while depletion of CD66b+ MDSCs restored T-cell proliferation [72]. The gene discussed is CEACAM8; the disease is B-cell non-Hodgkin lymphoma.