MYH7 and cardiomyopathy: All deletions located in the head domain have been associated with cardiomyopathy, except for one recent case report by Ko et al. [22] that describes a 33-year-old female with early-onset muscular weakness and severe kyphoscoliosis and who possesses the same MYH7-mutation (p.Glu500del) as we found in our patients.