EGFR and lung adenocarcinoma: The EGF receptor (EGFR), a Receptor Tyrosine Kinase (RTK), a key driver molecule of lung adenocarcinomas [99], and its expression has been found to negatively correlate with hTid-1 expression levels in both lung adenocarcinoma cell lines, and in paired tumor and adjacent normal tissues from 55 patients with adenocarcinoma.