Immunohistochemical assay showed that 31/42 cancer tissue samples (73.81%) were positive for FZD7 and 8/42 paracancerous tissues samples (16.67%) were positive for FZD7, with mean IHC scores of 8.2 ± 3.5 and 2.7 ± 3.2, respectively (P < 0.05). This evidence concerns the gene FZD7 and cancer.