CD36 is a scavenger receptor expressed in multiple cell types, mediates lipid uptake, immunological recognition, inflammation, molecular adhesion, and apoptosis, and binds thrombospondin-1 (TSP-1), resulting in attenuation of angiogenesis and induction of apoptosis/blocking the vascular endothelial growth factor receptor 2 (EGFR2) pathway in tumor microvascular endothelial cells [84]. This evidence concerns the gene THBS1 and neoplasm.