On the molecular level, we detected the significant increases of CKAP2 protein (Fig. S1D) and mRNA (Fig. S1E) expression in DLEU1-overexpressing MCF7 cells, supporting the association between DLEU1-induced up-regulation of CKAP2 and the enhanced malignancy of breast cancer cells. The gene discussed is CKAP2; the disease is breast carcinoma.