In contrast to the high BRD9 degrader sensitivity we observed for B-ALL lines, human T-ALL cell lines, including PF-382, Jurkat, CCRF-CEM, DND-41, HPB-ALL, KOPT-K1, and MOLT-4, were insensitive in terms of growth inhibition (Supplementary Fig. 6E–L). Here, KRT1 is linked to acute lymphoblastic leukemia.