Of note, QA-68 treatment leads to degradation of BRD9, but not the JQ1 target, BRD4, in leukemia cells, and washout of QA-68 leads to a reversal of BRD9 degradation effects but has no effect on BRD4 (Supplementary Fig. 8A, B). This evidence concerns the gene BRD9 and leukemia.