PRDX4 and neoplasm: Although its activity in mammals is compensated by other enzymes such as peroxiredoxin (PRDX4), ERO1 deficiency impairs VEGFA folding and secretion in highly aggressive triple‐negative breast tumours (MDAMB231*), curtailing the tumour angiogenesis and metastasis (Varone et al., 2021; Zito, 2013; Zito et al., 2012; Zito, Melo, et al., 2010).