Lower serum albumin concentrations were also found to be significantly associated with disease severity and adverse outcomes in COVID-19 patients p<0.001 [SMD -0.99 (95% CI -1.11 to -0.88)] by Paliogiannis et al., suggesting that assessment of serum albumin concentrations might assist with early risk stratification and selection of appropriate care pathways in severe COVID-19 patients with a poor outcome [49]. This evidence concerns the gene ALB and COVID-19.