CFHR3 and hepatocellular carcinoma: Because levels of miR-590-3p showed an opposite role in OS and DFS as compared to CFHR3 in HCC cases, we first determined the association between CFHR3 and miR-590-3p, and it showed that the levels of CFHR3 were negatively correlated with the levels of miR-590-3p in TCGA-LIHC dataset (R=-0.3672, p<0.0001; Figure 3C).