P2RX4 and amyotrophic lateral sclerosis: To go further in the understanding of the P2X4 pathophysiological cell-specific function and dynamic, conditional cell-specific P2X4KI or P2X4KO mouse lines expressing P2X4mCherryIN or invalidated for the P2X4 gene specifically in myeloid cells (macrophages and microglia) or in neurons should be useful to decipher time and cell-dependent P2X4 function as well as surface and intracellular contribution of P2X4 in ALS.