By re‐analysing the RNA‐seq datasets for 14‐3‐3 family members and Kaiso target genes (including CDH1, CCND1, CCNE1, MTA2, DLL1 and DAG1) from GTEx and CCLE [41, 42, 43, 44], we found that the mRNA level of 14‐3‐3σ mRNA was positively and most significantly correlated with that of CDH1 in both normal human tissues (n = 11 688, r = 0.60, P < 0.001 in Pearson correlation analysis) in GTEx datasets and cancer cell lines in CCLE datasets (n = 1156, r = 0.41, P < 0.001) (Fig. 6A; Fig. S4A). The gene discussed is CCNE1; the disease is cancer.