In particular, CB-839 (telaglenastat), another GLS inhibitor, has moved on to clinical trials and exhibits promise as potential drug for renal cell carcinoma (NCT03428217; Table 2), hematological malignancies (NCT03428217 and NCT02071888; Table 2), non-small cell lung cancer (NSCLC) (NCT02071862; Table 2), and even those drug-resistant tumors (NCT03944902 and NCT03798678; Table 2). The gene discussed is GLS; the disease is non-small cell lung carcinoma.