Namely, Prepuberty cancer cells were enriched in Hallmark Interferon alpha response and Hallmark Interferon gamma response; DCIS cancer cells were enriched in Hallmark IL6-JAK-STAT3 signaling and TNFA signaling via NFKB; Tumor1 cancer cells were enriched in Hallmark angiogenesis, KRAS-up and DNA repair; Tumor2 cancer cells were enriched in Hallmark E2F targets and MTORC1 signaling (Supplementary File 2). The gene discussed is IL6; the disease is cancer.