ATG16L1 and Alzheimer disease: In addition to the 6p21.32 (HLA-DRA, rs9270599), two of the identified loci: at 8p21.1 (near SCARA3), and 2q37.1 (near ATG16L1) have been reported for AD (SCARA335, ATG16L121,32,36), and GIT traits (SCARA3: gastric or stomach ulcer37, ATG16L1: IBD38, ulcerative colitis and Crohn’s disease33,39).