We found that the Omicron BTI group had an inflammatory signature compared to HD characterized by an increase of PF4 (CXCL4, released during platelet activation, p < 0.0001), MPO, GDF-15 and LBP (associated with granulocyte activation, tissue damage and monocyte activation; p < 0.0001, p = 0.0229, p < 0.0001 respectively), and an increased lymphocyte/monocyte ratio (Supplementary Fig. 2c–e). This evidence concerns the gene GDF15 and Huntington disease.