IGHG3 and infection: Indeed IgG3, C1q, FcRIIa, FcRIII, OPA targeting MSP2 and IgG1, FcRIIa and FcRIII and OPA targeting AMA1 were all associated with increased odds of infection despite adjustment for age, current infection and household mosquito exposure (Fig. 6B, Supplementary Table S4).