TFE3 and renal cell carcinoma: Xp11.2 translocation RCC is characterized by the translocation on chromosome Xp11.2 and a gene fusion between TFE3 and several different genes, including ASPL (17q25), CLTC (17q23), NonO (Xp12), PSF (1q34), and PRCC (1q21) [8].