Similarly, IL-7 stimulation also promoted sCD127 mRNA level both in peripheral CD8+ T cells from melanoma patients (1.00 ± 0.14 vs. 0.79 ± 0.19; P = 0.0004, Fig. 2f) and controls (1.42 ± 0.19 vs. 1.10 ± 0.09; P = 0.0003, Fig. 2f), as well as in tissue-infiltrating CD8+ T cells from tumor tissues (1.00 ± 0.13 vs. 0.69 ± 0.12; P = 0.0005, Fig. 2g) and para-tumor tissues (1.02 ± 0.07 vs. 0.79 ± 0.11; P = 0.0006, Fig. 2g). Here, CD8A is linked to melanoma.