ALB and chronic kidney disease: In our study, our results suggested that reduced blood albumin levels (less than 3.4 g/dL) were associated with higher risk of 1-year mortality among ICU patients with CKD, while the significant association disappeared in CKD patients with albumin levels ≥ 3.4 g/dL, which is consistent with previous conclusions that HAE can be regarded as good prognostic factor for predicting risk of long-term all-cause mortality [30–38].