Our logistic regression analysis revealed that reduced albumin (for albumin-1st, OR = 1.885, 95% CI 1.474–2.412, P < 0.001; for albumin-max, OR = 1.530, 95% CI 1.201–1.949, P < 0.001; for albumin-min, OR = 1.868, 95% CI 1.466–2.379, P < 0.001) levels were related to lower risk (Odds Ratio, OR) for CV complications in Model 3 after all covariates including age, gender, insurance, ethnicity, hypertension, diabetes and malignant tumor were controlled (Table 2). The gene discussed is ALB; the disease is hypertensive disorder.