Similarly, the protein level of EMX1 was decreased in SCG tissues (Figure 1e), and it also showed a decreasing trend as the tumor grade increases (Figure 1f) (WHO I vs WHO II: p = .0066; WHO I vs. WHO III: p = .0003; WHO I vs. WHO IV: p < .0001; WHO II vs. WHO III: p = .0109; WHO II vs. WHO IV: p = .0003; WHO III vs. WHO IV: p = .0424). The gene discussed is EMX1; the disease is neoplasm.