As an important component of cystine transport protein Xc− (system Xc−), SLC7A11 has been found to inhibit ferroptosis by promoting cystine transport, increasing the intracellular cysteine level and GSH level (Jiang et al., 2015; Koppula et al., 2021), and also SLC7A11 has been considered to be a poor prognosis factor for endometrial cancer (Martin et al., 2022). This evidence concerns the gene SLC7A11 and endometrial cancer.