Many signaling pathways have been considered to be involved in the development of endometrial cancer, such as mitogen activated kinase-like pathway (MAPK), DNA repair process, PI3K-Akt pathway, steroid hormone receptors-associated pathway, WNT pathways, L1 cell adhesion molecule interaction pathway (L1CAM), and ferroptosis pathway (López-Janeiro et al., 2021). Here, L1CAM is linked to endometrial cancer.